Best Liver Detox Supplement-Reviews and Buying Guide

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Written By Mark

Meet Mark Smith, a product review writer with over 5 years of experience in consumer technology and home appliances.







The liver is the body’s largest organ and plays a crucial role in many bodily functions. It helps filter impurities, produce bile (which breaks down food), store glycogen (a form of sugar for energy) and synthesize hormones like insulin. If you drink alcohol or take medications regularly, your liver may struggle to keep up with its job. Luckily there are many natural supplements available that can support healthy liver function. Some common ingredients include milk thistle extract, turmeric root extract, artichoke leaf extract, and burdock root extract.

Here are the best liver detox supplement available on the market today.

Editor’s Pick-Liver Detox Supplement

Best Liver Detox Supplement Reviews In 2022

1. Liver Cleanse Detox & Repair Complex

Helping your liver cleanse itself is the first step to achieving a healthy and active lifestyle. Our Milk Thistle Complex includes milk thistle extract capsules, which are enriched with yarrow chicory root powder chanca piedra berberine and other ingredients for deep liver cleansing.

Maintain Normal Liver Function

Silymarin milk thistle with choline bitartrate helps you to maintain normal liver function. The herbs in this formula support your body’s natural processes for overall liver and kidney health.

Detox & Repair Complex

Before your liver starts feeling sluggish, try our Liver Cleanse Detox & Repair Complex. Using milk thistle seed extract and dandelion root powder, ginger root powder, turmeric root, and yarrow, we can help you boost your energy while protecting and nourishing your liver.

2. Liver Cleanse Detox & Repair Formula

Keep your liver healthy and clean with our powerful 100% plant-based formula. Our formula provides the key botanicals necessary to help promote liver function, including Milk Thistle, Artichoke, Choline, Dandelion Root, Alfalfa, and more. With a unique blend of natural ingredients found in nature to promote healthy liver function, The Liver Cleanse Detox & Repair Formula helps support detoxification pathways for optimal health and wellness.

Hangovers And Cholesterol Levels

Milk thistle extract as the main ingredient promotes the production of new liver cells, repairing and nourishing damaged livers, and supporting hangovers and cholesterol levels. The liver is the largest internal organ in our bodies. It performs more than 500 functions, including protein synthesis, detoxification, and hormone production. This powerful formula is designed to heal damaged liver cells, reduce inflammation and support healthy cholesterol levels.

Detoxify And Repair

A comprehensive liver cleanse formula to support your liver’s natural ability to detoxify and repair, while helping you feel your best. This gentle daily cleanse is made in a GMP-certified facility in America and third-party safety tested for purity. It contains herbal extracts, amino acids, and choline to support memory, mood and other brain functions.

3. Dr. Tobias Liver 21 Day Cleanse

The liver is the body’s primary filter, clearing waste materials from cells and blood. It also removes hormones and other chemicals that are toxic to the body. When your liver becomes overloaded with toxins, it can become inflamed and overactive. Liver supplements can help cleanse excess toxins from the body, allowing your organs to function more effectively.

Support Possible

A healthy liver is essential to your overall health. That’s why our Liver 21-Day Cleanse is expertly formulated to help cleanse and repair the liver, giving it the best support possible. By harnessing the power of chloroplasts, the engine of photosynthesis in plants, Solarplast provides a high concentration of energy molecules in every dose. All these ingredients come together to support the digestion of proteins and fats, supporting liver health.

Liver And Its Function

Dr. Tobias Liver 21 Day Cleanse is a natural solution for flushing the liver and its function. Created by doctor Tobias, this supplement utilizes Solarplast, which attacks harmful oxidants that can damage cells and cause premature aging. It contains no artificial ingredients, fillers, or binders.

4. NatureWise Liver Detox Cleanse Supplement (60 servings)

Your liver is one of the hardest-working organs in your body, crucial for healthy digestion, metabolism, and internal cleansing. It works like a filter to help eliminate harmful toxins from the body, protecting all of your vital organs from damage. Common toxins from our everyday modern lives, such as alcohol, poor diet, medications, and environmental toxins, put extra stress on the liver. When the liver becomes overworked, toxins accumulate in your body, throwing your health off balance.

Liver Balance Complete is a comprehensive complex of three herbal blends that help detox, strengthen, and protect your liver for long-term health. It includes time-tested herbs that help remove excess toxins, boost liver function, repair liver damage, and improve the liver’s resistance to stressors so that it can stay healthy — and keep you healthy — under the toxic load of modern life.

Strengthen Your Liver

Your liver works around the clock to help defend you from toxins common in everyday life, working like a filter to remove these harmful substances from your body. Our liver strengthening blend helps boost liver function and repair liver damage so it can continue doing its job well. Milk Thistle, Picrorhiza Kurroa, and Turmeric are powerful herbs that help rebuild liver cells and strengthen the liver against toxins while neutralizing certain toxins in the body to reduce stress on the liver.

Protection from Our Toxic Load

According to the National Resource Defense Council, more than 80,000 chemicals are currently used in the United States — many of which are potentially toxic. Our toxic load is increased further by poor diet, chronic stress, alcohol consumption, and medications. Our protective herb blend includes Bupleurum Chinense Extract, Kudzu Root Extract and Peony Extract, Traditional Chinese herbs which have been used for thousands of years to lighten the liver’s toxic load and prevent damage from toxins.

5. HUM Wing Man – Liver Detox Supplement – Milk Thistle Enhances

After a long day of work or play, you need a little help recharging your body and mind. But sometimes, the liver takes the brunt of what’s going on in your life. Our milk thistle supplement aids the liver as it eliminates toxins with the help of a powerful antioxidant blend. Supplementing with Hum Wing Man Milk Thistle helps prevent oxidative damage and supports overall liver health, bile flow, and detoxification.

Liver Cleanser And Detoxifier

HUM’s Wing Man Liver Detox Supplement is not only a liver cleanser and detoxifier, but it also helps improve the health of your liver. Each bubblegum-flavored tablet contains a unique blend that features artichoke leaf and dandelion root for added support. SUPPORT: Milk Thistle has long been known to help maintain healthy liver function, support a healthy immune system, and protect against free radicals from daily stressors.

Main Ingredients Of This Formula

Milk thistle and Dandelion root are the main ingredients of this formula, which support detoxification by supporting the regeneration of liver tissue and normalizing liver function. Artichoke extract supports overall health and is also known to support healthy bile flow.

6. Irwin Naturals Liver Detox & Blood Refresh Powerful Herbal Whole-Body Cleanse 

Liver Detox & Blood Refresh is a multi-pronged formula designed to assist your body in combating the accumulation of impurities resulting from lifestyle factors and environmental exposures.* This formula includes powerful liver support and traditional blood-tonifying botanicals that can help support your health when you need it the most.

Since 1994, Irwin Naturals has formulated supplements that address a wide spectrum of health needs and help set the new gold standard in the industry.

Our Mission

Develop best quality supplement products at affordable prices, focused on superior potency, bioavailability, and absorption. Our extensive line of 100+ supplements uses an all-liquid soft-gel delivery that offers superior advantages over hard tablets and capsules that are often hard to digest. Plus, our signature BioPerine Complex enhances nutrient absorption and potency. Our goal is to bring you targeted formulas with quality ingredients at effective levels.

Patented BioPerine for Superior Bioavailability

Our research team has sourced BioPerine, an extract of black pepper, to enhance the bioavailability and absorption of many nutraceuticals. Irwin Naturals’ Liquid Soft-Gels take BioPerine one step further by combining it with a powerful ginger extract for enhanced digestion. BioPerine is a registered mark of Sabinsa Corporation.

Beneficial Oils

We use beneficial oils appropriate for given formulas (including fish, flax, evening primrose oil, pumpkin seed, MCT oil, coconut, hemp seed, chia seed, avocado seed, and extra virgin olive oil)

Liquid Soft-Gels

The nutrients in our easy-to-swallow Liquid Soft-Gels are released fast. Other delivery forms can contain binders and fillers that may cause stomach upset and offer no nutritional value. Advanced Liquid Soft-Gels provide an optimum delivery system.

7. Liver Detox & Support Supplement

Modern lifestyles and busy schedules have us straining ourselves to breaking point. The human liver, the one organ responsible for flushing out toxins and keeping your body healthy & well balanced, is one of the first organs to take a hit when you are not on a healthy diet. Here are some common signs of failing liver health.

Most Powerful Things

Detoxifying your liver and supporting its health is one of the most powerful things you can do to keep yourself feeling energized and healthy. Simply Potent has created the ultimate liver support supplement with 22 herbs that offer incredible benefits in just 30 days. Our proprietary blend combines milk thistle, artichoke, beetroot, and other superfoods so you can detoxify your liver naturally with food-based ingredients. Get yours today!

Powerful Antioxidant

This product contains a blend of herbs and other ingredients that have been shown to help promote liver health. It includes Chanca Piedra, which helps soothe liver cell damage; Juniper Berry extract, which has antioxidant properties; Turmeric, which is a powerful antioxidant and helps protect the liver from toxins; Ginger Root helps support liver function, Artichoke Extract aids bile production; Beetroot aids liver enzymes & grape seed extract aids fatty liver; Chicory Root prebiotic fibers benefit digestion; Yellow Dock is rich in nutrients that help detox the liver & pine mulch supports eye & skin health.

8. Liver Detox Supplement by Ancient Nutrition

Liver Detox Supplement by Ancient Nutrition provides targeted support for healthy liver function and a healthy response to inflammation. This premium liver support formula contains milk thistle seed, dandelion root and reishi as well as botanicals and adaptogens to help support detoxification. With this formula, you’ll get all the nutrients you need for optimal liver function, including a full spectrum of vitamins, Amino Acids, Phytonutrients and Antioxidants for proper antioxidant support.

Helps Promote Healthy

Liver Detox is a standardized herbal supplement that helps promote healthy liver function. This formula supports your body’s natural detoxification processes and eliminates harmful toxins, heavy metals, and other poisons from your liver. Liver Detox supports a healthy mental state by gently easing symptoms of depression and anxiety.

Body Of Harmful

Ancient Nutrition Liver Detox is designed to help rid your body of harmful toxins and support your liver by filtering, removing, and detoxifying. This formula can help you on your ketogenic journey by helping to remove unwanted metabolites from the body produced when we break down food into energy on a ketogenic diet.

9. Quicksilver Scientific Liver Detox Sauce

Quicksilver Scientific Liver Detox Sauce offers a premier liver support formula that simultaneously assists all cleansing and toxin elimination phases. Liver Detox Sauce utilizes a proprietary blend of powerful ingredients to assist the body’s natural detoxification process.

Classic Drainage Botanicals

Quicksilver Scientific Liver Detox Sauce is a premium blend of four classic drainage botanicals–dandelion, solidago, gentian, and myrrh. It also contains methylsulfonylmethane (MSM), silymarin (from milk thistle), R-lipoic acid (RLA), and diindolylmethane (DIM), quercetin, and luteolin.

Healthy Immune Function

Liver Detox Sauce provides powerful herbal support for your liver, supporting healthy immune function, promoting healthy weight management, and helping to maintain a calm and stress-free environment throughout the system.

10. Liver Detox Cleanse – Liver Cleanse Detox & Repair

Liver Cleanse Detox & Repair Supplement is a powerful supplement that supports liver health and vitality. With a team of herbs that may detoxify malignant toxins and protect liver cells from damage, this cleanse can help you care for your entire body, including your most important organ: the liver.

Health And Cleanse Toxins

Liver Detox Cleanse provides an all-natural way to support your liver’s health and cleanse toxins from your body. This formula supports the growth of new liver cells, helps protect against irritants to the liver, and restores a healthy balance of hormones that are fundamental to proper organ function.

Organic Turmeric Root

This Liver Detox & Repair formula includes Silymarin Milk Thistle Seed Extract, Organic Turmeric Root, Organic Burdock Root, Organic Beet Root Juice Powder, Artichoke Extract, Dandelion, and Chanca Piedra. The product uses organic herbs to help cleanse the liver and remove toxins from the body. It also helps with digestion and gives your skin a healthy skin glow.

How To Choose The Best Liver Detox Supplement Before Purchasing


It is imperative that liver health supplements are made with proven ingredients. Studies have shown that vitamin, mineral, and plant extracts can significantly impact liver health. These supplements were tested and proved scientifically before inclusion in this guide.


The wrong dosage is what keeps some manufacturers from getting the right ingredients. Many liver health formulas on the market are very low in dosages, making them almost harmless to the body. On this list are formulas that are clinically effective for liver health.

Doctor Formulated

Health professionals, including medical doctors and naturopathic physicians, nutritionists, and others are often part of the advisory boards for large and reputable supplement companies. They offer the best liver health supplements based on their medical expertise. This list contains several liver health support formulas formulated by doctors.

Advertised Benefits

Supplements for liver health commonly overstate their benefits. According to them, their supplements can remove all toxic waste from the body. Another company claims their product is able to reduce weight by fifty pounds, make users look ten years younger, and heal liver disease. In all these cases, consumer spending is being induced by exaggerated and unrealistic statements. This list consists of supplements that are honest about their health benefits.


Several companies produce high-quality supplements. The industry has seen the entry of other manufacturers who aren’t stable. Some companies provide accurate information regarding ingredient sources, manufacturing locations, and dosages, while others lie. We have included supplements for liver health from reputable and legitimate companies in this guide.

Price and Value

A supplement to support liver health may cost some consumers $100 or even more, while others will spend only $20 or less. There are supplements in this list to suit various budgets without sacrificing value. This ensures that every dollar spent on ingredients is well spent.

Milk Thistle

Most liver health support supplements contain an ingredient like this. An active ingredient called silymarin in milk thistle helps generate liver tissue, combat inflammation, and protect liver cells. Antioxidant properties are also provided by it.

Artichoke Leaf

In many supplements for liver health, this ingredient is also widely used. A few studies have shown that it also exhibits antioxidant properties that may help protect the liver. According to studies, it regenerates liver cells. Conversely, some have found that treating patients with non-alcoholic fatty liver disease reduced markers of liver damage.

Dandelion Root

Several of these supplements contain this ingredient. Dandelion’s ability to support liver health is less studied than that of milk thistle extract or artichoke leaf. Despite its antioxidative, anti-inflammatory, and anticarcinogenic properties, many researchers have studied dandelion.


In addition to its many benefits, zinc is an essential mineral for immune function and DNA synthesis. The risk of developing zinc deficiency among chronic liver disease patients is higher.

Licorice Root

Many liver health supplements contain this popular natural extract. It has been linked to a reduction in hepatitis C infection in some scientific studies. Licorice root has also been shown to reduce liver fat accumulation and inflammation caused by alcohol. These benefits need to be confirmed in humans, as this study was conducted on rats.


It is primarily used to treat inflammation. For liver health, it is commonly taken daily. There are multiple ways turmeric supports liver health by containing curcumin.

Yellow Dock Root

Even though studies have linked it to various liver benefits, this ingredient is relatively unknown. Traditionally used for blood cleansing, yellow dock root is frequently available in the Essiac tea recipe. Some studies suggest it has detoxifying effects, while others suggest it has diuretic effects.

Frequently Asked Questions

What Is The Appearance Of Stool With Liver Problems?

It may indicate that the liver or other parts of the biliary drainage system are malfunctioning if the stools are pale. Blood from the stomach and intestinal tract can result in black tarry stools, which should be treated by a physician as soon as possible in advanced liver disease.

Are Lemons Good For Detoxing Your Liver?

It is not enough just to drink lemon water to detoxify. We can flush toxins out of our bodies by drinking lemon water. You’ll also need fiber to flush your system because lemons, despite the high levels of Vitamin C, are not high in fiber.

When The Liver Is Ailing, Where Does It Itch?

Itching commonly occurs among patients with chronic liver disease, particularly patients with primary sclerosing cholangitis (PSC) and PBC, which are cholestatic liver diseases. A patient is typically itchy on the soles of their feet and the palms of their hands.

Is The Liver Affected By Sleeping Late?

In addition to affecting the ability of the liver to produce glucose and process insulin, losing a single hour of sleep may also increase the risk of metabolic diseases such as hepatic steatosis (fatty liver) and type 2 diabetes.


The most important thing to remember about a liver detox is that the best results come from taking it consistently. It may take longer, but you can rest assured knowing your body will be healthier in the long run if you stick with it. In addition, there are many ways to help flush out toxins naturally and safely without resorting to harsh chemicals or drugs – so don’t give up! We have compiled some of our favorite natural methods below for anyone looking for more ideas on how they can better clean their liver organically.

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