Best Hyaluronic Acid Supplement (Reviews Updated 2022)

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Written By Mark

Meet Mark Smith, a product review writer with over 5 years of experience in consumer technology and home appliances.







Hyaluronic acid is a natural substance that lubricates the skin, joints, and eyes. Over time, the level of naturally-occurring hyaluronic acid decreases. When combined with osteoarthritis – the lack of this crucial lubrication can cause pain and inflammation. It is a gel derived from plants and used as an anti-aging treatment.

Here are the best hyaluronic acid supplement on the market.

Editor’s Pick-Hyaluronic Acid Supplement

Best Hyaluronic Acid Supplement Reviews In 2022

1. NatureBell Plant-Based Hyaluronic Acid Supplements

Hyaluronic acid (HA) is a compound found naturally in our skin that holds water and helps keep it hydrated and plump. It is the key to instantly plumping fine lines and making skin look glossy. It can be found in everything from serums to sheet masks and even injectables

Oxidative Aging

Hyaluronic acid may support protection by releasing antioxidants to prevent the effects by free radicals. Additionally, we also add Vitamin C in it, which is known as a powerful antioxidant.

Skin Dryness and Hair

Hair, and nail: Hyaluronic Acid may support hydrating your skin. It is a good choice to soothe your skin by using our Hyaluronic acid. It also may support your nails and hair.

Joint Lubrication

Hyaluronic acid may support binding well to water, producing a viscous, jelly-like consistency. This viscous fluid provides lubrication and acts as a shock absorber within the joint.

2. Hyaluronic Acid Supplement

Hyaluronic acid, sometimes referred to as hyaluronan, is a clear viscous substance naturally produced by the human body. The largest amount is found in skin, eyes, and connective tissue. It’s primary function is to retain water and keep your tissues well lubricated. Supplementing your body’s natural store of hyaluronic acid with a serum and capsules can provide many benefits. Hyaluronic acid capsules work best with a hyaluronic serum or cream for face or skin. Double Wood’s Hyaluronic Acid Capsules are Made / Tested in the USA, Non-GMO and Gluten Free.

Hyaluronic Acid Supplement

Hyaluronic Acid is a natural substance found in your body. It’s also found in many foods and dietary supplements, including certain moisturizers and creams. The Hyaluronic Acid Supplement by Double Wood is made with no additives or preservatives. This supplement delivers potential benefits to your skin and joints faster and with ease, without preservatives or additives.

Prompt Results

Hyaluronic Acid Supplements are best when paired with a hyaluronic acid serum or cream but can also be taken on their own. Our Hyaluronic Acid Supplements have given prompt results without being harsh on the body. At Double Wood Supplements, our goal is to create an industry standard in which supplements are focused on delivering vegan-friendly, natural results without using artificial preservatives or additives.

3. Hyaluronic Acid Supplements 200mg

Hyaluronic acid capsules are made from pure hyaluronic acid powder (derived from plants), making them vegan-friendly and suitable for vegans and vegetarians. They are also free from lactose, gluten and artificial ingredients. The capsules are made in the USA, the packing is recyclable and the capsules themselves are BPA free. One bottle contains 12 capsules worth of hyaluronic acid, which will last 4 months at 2 capsules twice a day.

Maximum Hair, Skin, and Joint Support

As we age, our production of hyaluronic acid starts to decrease. Our pure hyaluronic acid product gives you natural overall body hydration. It promotes hydration for important things like hair, skin, and joints. Leaving you feeling refreshed.

Special Fermented Source

The body naturally produces hyaluronic acid, so we wanted to make a form that is best accepted by the body. We use a special fermentation process that produces natural, high-quality hyaluronic acid. Giving you a highly potent product can be absorbed by the body more efficiently.

Pure Ingredients

We get our hyaluronic acid from pure sodium hyaluronate. This is the primary component that makes up the hydrating effects that come from hyaluronic acid. Giving you an extremely hydrophilic product. This means it absorbs better and attracts more water.

4. Premium Hyaluronic Acid Supplements 250mg

Benevolent Nourishment’s Hyaluronic Acid is formulated to restore volume to sagging skin while locking in moisture for a younger look. Enhanced with L-Proline and Vitamin C, these beneficial ingredients contain restorative properties that truly transform your skin. HA also helps increase the water retention in your skin to help reduce the appearance of wrinkles and fine lines for an even more flawless complexion.

Hyaluronic Acid Is Special

As we age, our skin loses moisture, becoming less firm and elastic. Hyaluronic Acid is special because it can hold in moisture more than any other natural or synthetic polymer. Benevolent Hyaluronic Acid supplement bottle contains 120 veggie capsules giving you a 2-month supply of this 3-in-1 Hyaluronic Acid supplement to aid you in achieving clearer skin, stronger joints & a younger-looking you!

Quality, And Affordable

Benevolent Nourishment’s sole purpose is simple: to provide ethically sourced, quality, and affordable products to a complicated world. Customers immediately recognize our products because they are made with integrity and work.

5. Liposomal Hyaluronic Acid Supplements for Women

Whether you’re seeking relief from aches and pains or want to improve your skin’s health, our Liposomal Hyaluronic Acid supplements are the perfect option. Our high-strength formula provides ten times the quantity of hyaluronic acid as other brands, plus we’ve included just a small amount of vegetable oil to carry it through the body via liposomes – an exceptional delivery form. This allows our hyaluronic acid molecule size to be 500-700 kDa which has an exceptionally high level of bioavailability.

Spherical Molecular Structure

Liposomal Technology Simplified: The liposome is a spherical molecular structure with a phospholipid membrane and an inner aqueous compartment. Unlike regular sublingual pills, which pass through your digestive tract into the bloodstream, our amazing new Hyaluronic Acid supplement is absorbed directly through the mucosa tissue of your mouth, where it binds with moisture to give you that glowing look!

Acid Pills Or Powder

Hyaluronic acid acts as a “hydrator” and plays a vital role in the skin, hair, nails, joints, and eyes. With superior absorption compared to regular hyaluronic acid pills or powder, our liposomal hyaluronic acid soft gel capsules can help you reach optimal levels of hyaluronic acid sooner.

6. Obvi Collagen Pills, Multi Collagen, and Hyaluronic Acid Supplement

Obli Collagen is a premium formula containing Colostrum, Collagen Type II, Hyaluronic Acid, and Vitamin C. Over 20 studies have shown that this powerful combination supports healthy collagen production in your body and provides some serious anti-aging benefits.

Supplement Containing Collagen

Overeating, sedentary lifestyles, and nutritional deficiencies can all damage the joints. The best way to combat this is by taking a supplement containing collagen and hyaluronic acid. This product uses a patented formula of both these ingredients to support healthy muscles and joint function.

Obvi Collagen Pills Contain

Get healthy and thicker hair with the #1 selling collagen supplement. Obvi Collagen Pills contain a high dose of collagen and hyaluronic acid to support your hair growth. Especially great for thinning or lackluster locks, this supplement is clinically proven to increase healthy hair growth in women within 30 days!

Uses for Hyaluronic Acid Supplements


One substance that aids in moisturizing the joints is hyaluronic acid. People with severe knee osteoarthritis may temporarily relieve pain and stiffness after receiving an injection of hyaluronic acid, known as hyaluronan. Hyaluronic acid injections are occasionally used to control symptoms but are not regarded as first-line therapy for knee osteoarthritis.

Less is known about the advantages of hyaluronic acid taken orally. Nevertheless, several tiny studies have offered hope.

According to a 2015 study in Rheumatology International, persons with obesity and knee osteoarthritis found alleviation from their conditions after taking Oralvisc for three months.

5 In individuals who received Oralvisc, researchers discovered:

Improved standard of sleep

Compared to individuals who received a placebo, there was a significant decrease in the usage of painkillers (a treatment with no medical benefit)

Rough skin

There is proof that oral hyaluronic acid has antiaging qualities that enhance skin tone and lessen wrinkles and fine lines.

A 2022 study published in Clinical, Cosmetic, and Investigational Dermatology found that after 12 weeks of oral hyaluronan therapy, the depth and volume of 60 people’s crow’s feet (wrinkles in the corner of the eyes) decreased. They also have more suppleness and gloss to their skin. The study employed two distinct hyaluronan concentrations, each dosed at 120 milligrams (mg) per day. Interestingly, persons who received the higher concentration had outcomes similar to those who received the lesser dose, but they did so faster.

Similar encouraging results were revealed by a 2022 study published in the Journal of Evidence-Based Complementary and Alternative Medicine on hyaluronic acid supplements comprising biotin, vitamin C, copper, and zinc. In particular, the study discovered that 20 women aged 45 to 60 had:8.

Hyaluronic acid is a lubricant and aids in fluid retention. Thus, people with dry eye illness increasingly use eye drops that include this substance.

Evidence suggests that this may be an effective strategy for those with dry eyes. In a 2021 study, participants using hyaluronic acid-containing eye drops produced much more tears than those using drops without the substance. 9

Additionally, compared to cases where saline drops were administered, the tear breakup time—a metric used to diagnose dry eye syndrome—significantly improved after using the hyaluronic acid-containing drops. Researchers discovered that hyaluronic acid drops were more effective at treating dry eye symptoms and signs than other types of artificial tears. 9

Knee Pain

Another benefit of hyaluronic acid use is that it may lessen joint pain. This substance has anti-inflammatory properties, lubricates the joints, and guards against the constriction of the joints that can happen with arthritis.

Many people who experience joint problems can relieve pain through hyaluronic acid. An analysis published in the Nutritional Journal in 2016 found that oral hyaluronic acid, also known as hyaluronan, was beneficial in reducing knee discomfort and inflammation and even aided in the recovery of localized muscle strength.

Eight of the trials looked at in the study reported a substantial decrease in only knee pain.

Reflux of Acid

The esophagus may get irritated when stomach acid intended for digestion travels back up the digestive tract (food tube). The symptoms of acid reflux, commonly known as gastroesophageal reflux disease (GERD), can range from a dry cough to esophageal injury to teeth erosion.

Hyaluronic acid appears to have a part in managing such acid reflux. The following symptoms of reflux were reduced when hyaluronic acid and chondroitin sulfate were combined, according to a 2019 study published in Otolaryngology.

Frequently Asked Question

When should I take hyaluronic acid?

Moisturizers and serums are two of the most common forms of hyaluronic acid. Moisturizers. Use a moisturizer infused with hyaluronic acid at the time when you’d usually moisturize. Ideally, this would be 2 times a day after cleansing, exfoliating, or applying serums.

Can vitamin C be taken with hyaluronic acid?

Can You Use Hyaluronic Acid and Vitamin C Together? Not all powerful skincare ingredients can be mixed, but hyaluronic acid and vitamin C are two that become even stronger when paired with one another. These ingredients can provide immediate and lasting results when used in anti-aging formulations.

How long does hyaluronic acid take to work for joints?

Everyone responds to hyaluronic acid injections a little differently. You might have almost immediate relief, or it could take a few weeks for the inflammation and pain in your knees to subside. Soon you find that you can move more easily and without pain. Most patients have pain relief for 4-6 months.

How can I increase hyaluronic acid in my body?

Adding bone broth to your diet is a great way to increase your intake of hyaluronic acid. Plus, foods such as soy products, oranges, almonds, kale, and sweet potatoes provide nutrients that may naturally ramp up your body’s hyaluronic acid synthesis.

Is retinol or hyaluronic acid better?

Hyaluronic acid is best if they’re looking to moisturize dry skin, while retinol works better by encouraging better skin by boosting collagen production. They have several benefits that can work in tandem for better results, though patients need to be careful with their exact formulations.


If your goal is to treat the symptoms associated with aging, it’s worth adding a hyaluronic acid supplement to your vitamin regimen. Our research has found that these supplements are relatively safe and effective for most people. Of course, talk to your local doctor for advice about which supplements will work best for you.

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