Best Glycine Supplement

Proper nutrition is something that all of us should be concerned with. This includes a wide range of topics, from the kind of food you eat to supplementation to your overall body composition. A common question that arises among many individuals is how to choose the best glycine supplement. By comparing and contrasting several different options, we can begin to see what options might be the most appropriate for you.

Best Glycine Supplement Reviews

1. NeuroScience Calm PRT – Sleep Supplement with Glycine

Product BenefitsEnergy Management
Item FormCapsule
Item Weight0.3 Pounds
Unit Count90.00 Count
Item Dimensions LxWxH6 x 3 x 3 inches

Contains ingredients important for regulating the stress response, reducing anxiousness, and sleep.

NeuroScience formulates and organizes products into the network impacted within their multi-system approach: Catecholamine, NeuroAdrenal, NeuroImmune, and Serotonin/GABA.

Calm PRT is part of the NeuroAdrenal line.

The NeuroScience Approach

Holistic formulations with blended ingredients offer comprehensive support that individual ingredients cannot.

NeuroScience emphasizes the science behind symptoms and quality blended ingredients at impactful amounts, delivering consistent results. Formulations are based on published scientific journals and clinical studies that discuss safe and effective ingredients as well as the amount necessary for positive outcomes.

Growth Rooted in Neuroscience

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

2. NOW Supplements, Glycine Pure Powder

Product BenefitsEnergy Management
Item FormPowder
Dosage FormPowder
Age Range (Description)Adult
Material FeatureVegan
Item Weight1 Pounds
Unit Count16.0 Ounce
Item Dimensions LxWxH6 x 5 x 4 inches

Glycine is a non-essential amino acid and has the simplest structure of all amino acids, allowing it to fit easily within protein chains and make space for structurally larger amino acids. This feature makes it very important for specific bodily functions. Glycine is also a precursor of creatine, which is used to construct DNA and RNA. And it supports glycogen storage, thereby making more glucose available for energy production.* The amino acid Glycine is non-chiral and only has one form without a D- or L- designation.

Diet Supplementation

NOW Glycine Pure Powder is one of the ten standard amino acids and is used as a nutritional supplement. It is considered an essential amino acid, which means that it cannot be synthesized in the body and must be obtained through diet or supplementation. Glycine plays an integral role in protein synthesis, protein metabolism, and detoxification pathways. Recent research has also shown that glycine promotes restful sleep.

Improve Immune System

Glycine is an amino acid found in many protein-based foods. It supports healthy brain function, and immune system health and has a calming effect. In support of that mind-to-body connection, glycine promotes restful sleep.

3. Solaray L-Glycine, Veg Cap

Item FormCapsule
Age Range (Description)Adult
Material FeatureVegetarian
Item Weight0.22 Pounds
Unit Count60.00 Count
Item Dimensions LxWxH2 x 2 x 4.16 inches

Solaray L-Glycine is a non-essential amino acid that is used by the body for protein formation and helps support normal brain function. Glycerin also provides nutritive support for normal liver function, body fat metabolism, and normal blood sugar levels.

Provides Nutritive Support

Solaray L-Glycine supplies the body with glycerin, a non-essential amino acid that is used by the body for protein formation. Glycerin also provides nutritive support for normal liver function, normal brain function, and mental clarity.

Support Liver Function

Glycine is used by the body to help form protein and make the liver, muscle, and brain perform their functions. It is also a basic requirement for the maintenance of a normal nitrogen balance in the blood, which helps prevent fatigue and weakness. In addition, Glycine supports normal liver function, and mental clarity and may be useful in detoxifying heavy metals such as lead and mercury.

4. Puritan’s Pride Glycine Morning Grogginess

BrandPuritan’s Pride
Product BenefitsEnergy Management
Item FormCapsule
Material FeatureCaffeine Free
Unit Count90 Count
Item Dimensions LxWxH2.73 x 2.73 x 4.88 inches

Glycine 3000mg is a new solution to help with morning fatigue. This caffeine-free, stimulant-free formula works with your body’s natural metabolic processes to help reduce morning drowsiness and grogginess. Instead of reaching for another cup of coffee or an energy drink, incorporate Glycine into your daily routine to help you get going in the morning.

Reduce Morning Drowsiness

The morning is your most important time of day, but if you’re feeling groggy, it can be difficult to reach top performance. Now there’s a new solution to help with morning fatigue. Glycine 3000 mg is a caffeine-free, stimulant-free formula that works with your body’s natural metabolic processes to help reduce morning drowsiness and grogginess. Instead of reaching for another cup of coffee or an energy drink, incorporate Glycine into your daily routine to help you get going in the morning.

100% Natural Ingredient

Glycine is a unique 100% natural ingredient that helps with morning fatigue. By helping your body to burn fat, it is easier to get out of bed and ready for the day.

5. Country Life Glycine 500 mg

BrandCountry Life
Specific Uses For ProductPromotes Muscle Growth, Preservation of joints and cartilage
Product BenefitsAnti-aging,Energy
Item FormTablet
Diet TypeGluten Free
Dosage Form500-1000
Age Range (Description)Adult
Allergen InformationGluten Free
Material FeatureVegetarian

Country Life’s Glycine 500 is a quick and simple way to ensure an adequate supply of glycine in your diet. This low-cost vegetarian capsule is an excellent alternative for those who may be concerned about the use of animal extracts in supplements. Country Life’s Glycine 500 is made with 100% pharmaceutical-grade glycine, which is one of nine essential amino acids that must be consumed through foods or supplementation.

Improve DNA Synthesis

Country Life’s Glycine 500 mg is a great way to maintain healthy muscle growth. Along with helping to form collagen and improve DNA synthesis, Glycine plays a role in the production of proteins like creatine and carnitine, which have been found to have a positive effect on performance.

Growth And Repair

Country Life Glycine 500 mg provides 500 mg of pure glycine per capsule, which is the most easily absorbed form. This amino acid boosts muscle growth and repair while protecting joints and cartilage.

Provide Essential Amino Acid

Country Life Glycine 500 mg is a beneficial nutrient for overall body function. It works to help maintain lean muscle mass into old age, helps promote joint health, and aids in the production of neurotransmitters within the brain. Glycine is an essential amino acid that plays an important role in protein synthesis by serving as one of the building blocks for protein production.

6. Nature’s Life Prostate Maintain 600 Plus

BrandNature’s Life
Item FormCapsule
Dosage FormCapsules
Material FeatureVegetarian
Item Weight0.59 Pounds
Unit Count250.00 Count
Item Dimensions LxWxH3.2 x 3.2 x 6.2 inches

While we can’t stop aging, we can provide the nutritive support our bodies need to lessen the effects of growing older. Formulated to help support a healthy prostate, Nature’s Life Prostate Maintain 600 Plus includes amino acids and herbs used and trusted both traditionally and today!

For an Active You

Our Prostate Maintain 600 Plus formula begins with Active Aminos L-Glutamic Acid, L-Alanine & Glycine – the primary prostate proteins.

Herbal Tradition

Used for centuries to help support men’s health, our formula includes Saw Palmetto, Pumpkin Seed & Pygeum Bark.

More for Men

Lastly, Prostate Maintain 600 Plus provides Vitamin B-6, Zinc, and Copper – all important nutrients for proper prostate function.

Start with Nature

Start with NatureOur high-quality prostate support supplement is vegetarian, non-GMO, and lab verified for potency, purity, and identity.

Why Nature’s Life?

Since 1970 Nature’s Life has been providing high quality supplements that we’re proud to stand behind. We are committed to the wellbeing of our customers and everything we do is focused on helping our users achieve their optimal health.

Are glycine supplements safe?

Glycine is a generally safe supplement. This amino acid has been used in doses up to 60 grams per day without side effects. As a result, it is thought to be exceedingly difficult to overdose on glycine supplements. GI problems (abdominal heaviness and flatulence) are the most common side effects.
People who are undergoing treatment for significant psychiatric disorders, such as schizophrenia, should not use this product without medical supervision. Glycine supplementation may impair the function of clozapine-type antipsychotic medications in certain circumstances, aggravating the condition.

(Blood cells in charge of bleeding management and prevention) Individuals on anticoagulant or antiplatelet medicine, as well as those with congenital platelet problems, should see their doctor before taking glycine.

Finally, keep in mind that there is no evidence that these nutritional supplements are safe during pregnancy or lactation. As a result, women who are pregnant or breastfeeding should avoid using glycine supplements. Without previous physician approval, children under the age of eighteen should not take this supplement.

What are the advantages of taking a glycine supplement?

Glycine supplements are used to try to improve the well-being of consumers and patients in the fields of sports nutrition and medicine. When looking at human clinical trials, it’s clear that glycine supplementation offers three possible advantages:

Restful sleep:

Supplementation with glycine may help to promote and improve sleep.

Relief from fatigue

Supplementing with glycine has been proven to lessen fatigue in the subjects investigated. This benefit could simply be attributable to the improved sleep quality associated with glycine ingestion.

Neural Security:

Glycine supplements have been used in medicine to treat mental illnesses such as schizophrenia. Experts believe that this amino acid could help certain people improve their cognitive capacity by stabilizing neural function.
Supplementing with glycine will help you get the recommended daily amount (CDR) of this vitamin. Keep in mind that this amino acid is required for the production of collagen, a protein that provides bone strength and skin flexibility, among other things.

Buying Guide

If you’re thinking about adding a new glycine supplement to your diet, we recommend reading this section first. The less visible (but as significant) elements of glycine supplements will be the focus of our purchasing criteria. This allows you to select a product that is appropriate for your lifestyle.

  • Vegan Food
  • Intolerances and allergies
  • Format
  • Expiration and Conservation

Vegan Diet

Take a deep breath if you’re a vegan or vegetarian. Although animal products contain the most glycine, this amino acid is mainly acquired from plant sources in supplements. The majority of glycine nutritional supplements will be vegan. Avoid gelatin covers and go for cellulose-coated (vegetable) capsules.

Intolerances and allergies

Glycine allergies are extremely uncommon. Glycine is an important amino acid found in the body’s cells. However, intolerance reactions to other supplement components (additives and capsules) are possible. If you have soy, gluten, or nut allergy, read the ingredient list before purchasing.


Glycine supplements can be purchased in a variety of forms. Mixing powder (which allows you to choose a more tailored dose) and capsules are the most common (which simplify supplementation).

There are other newer formats that blend liquid and solid forms while also including additional nutrients (such as vitamins and minerals).

Creams and gels are another less well-known way to use glycine. This type is used to speed wound healing or to make ulcerative lesions look better. Unfortunately, in today’s market, locating these can be tough.

Expiration and Conservation

After a glycine supplement’s expiration date has passed, the amino acid will progressively lose its potency. Expired glycine supplements are generally discouraged by manufacturers. If the supplement’s quality is good, it can be used for a few more months without losing its effectiveness.

Keep your glycine supplement dry and away from high temperatures, direct sunshine, and strong scents. Check that the supplement bottle or container has been properly closed after usage. Avoid putting this product in contact with water (this is especially important in the case of powder).

FAQs: Glycine Supplement

How much glycine should I take daily?

Glycine: Is It Safe? At proper levels, glycine supplementation is safe. Glycine doses of up to 90 grams per day have been used in studies with no major negative effects ( 45 ). The typical dose used in studies is approximately 3–5 grams per day.

Is glycine a good supplement?

Glycine supplements may help reduce the chance of a heart attack, in addition to being associated with lower blood pressure and obesity risk. Glycine levels in the blood were linked to a decreased risk of a heart attack in a study of nearly 4000 persons experiencing chest symptoms.

Is L glycine the same as glycine?

The main distinction between glycine and L glycine is that glycine is an amino acid that is found in proteins, whereas L glycine is a glycine isomer. An amino acid is a glycine. It can be found in two structurally isomeric forms: D glycine and L glycine.

Can you take glycine long term?

Glycine has been linked to an increase in NMDA neurotransmission, and low levels of NMDA receptors have been linked to the development of schizophrenia. Glycine is a possible beneficial treatment for schizophrenia symptoms since it is safe for both short and long-term use.

Is glycine good for hair?

Glycine aids the correct functioning of the digestive system and the central nervous system, as well as hair development. This amino acid is particularly important because it protects the body against nerve abnormalities, which can lead to hair loss and other health issues.


In short, glycine is an important building block in the human body that can be useful for our functions and health. Food is not sufficient enough to sustain enough of this amino acid for the human body and we must take it as a supplement. Glycine comes in many forms such as glycerol (in skincare products), gelatin, and more, although synthetic glycine supplements are more popularly used in pharmacies and by nutritionists everywhere.

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