7 Best Choline Supplement For Fatty Liver

Choline is a well-known compound that is found in dietary supplements and it provides a wide variety of advantages to one’s overall health. Choline, for instance, is beneficial to cognitive function, the health of the liver, and the maturation of the brain in developing children.

The most significant benefit of choline supplements as a nootropic is seen in brain health regarding the production of acetylcholine, which helps to preserve memory and cognition while enhancing mental clarity.

If your body’s choline levels continue to drop without you noticing, it can put you at risk for a number of health problems. It is essential to maintain adequate levels of choline because choline deficiency can snowball into severe health problems later on, making it imperative that adequate levels be maintained.

Benefits of a Choline Supplement

With that said, choline supplementation may be an option for those who believe in choline’s importance and want to experience it for themselves (especially if they know they aren’t getting enough through their diet). Supplementing with choline has been shown to have numerous health benefits.

  • Improved brain function: Choline (citicoline, in particular) has been shown in studies to reduce dementia risk, improve cognition, memory, speaking ability, concentration, and reaction speeds, all while decreasing impulsivity. Improved brain function. Many individuals regard choline supplements to be nootropics in their own right because of these benefits [6,7,8].
  • Neurotransmitter manufacturing starting material: The amount of acetylcholine you can create depends in part on the amount of dietary choline you consume. The production of acetylcholine is critical for numerous bodily and mental processes, including muscular contraction, digestion, sweat gland function, mood, and memory [9, 10].
  • Precursor to DNA building block: Choline is a critical component of citicoline, a precursor to uridine, which is utilized in DNA synthesis—essentially implying that normal DNA synthesis isn’t feasible without enough quantities of choline [2].
  • Cholesterol management and liver health: The role of Choline in cholesterol management and liver health: Choline regulates cholesterol levels, and studies have shown that choline deficiency can lead to non-alcoholic fatty liver disease, which may cause irreparable liver damage if not treated. [1].
  • Cell membrane integrity: The integrity of the cell membrane is dictated by phospholipids like phosphatidylcholine, which are found in high concentrations in the cell membrane. The breakdown of cells, which cannot retain their integrity without choline, can cause muscle and liver tissue damage in as little as two weeks in persons who are truly choline deficient [1].

7 Best Choline Supplement For Fatty Liver- Reviews

Here are the top 7 Choline Supplements on the market today.

1. Alpha GPC 600mg + Uridine

Alpha GPC is a choline supplement often used to boost L-alpha glycerylphosphorylcholine, which is also known as phosphatidylcholine (PC). It’s thought to act similarly to the neurotransmitter acetylcholine in the brain. Alpha GPC 600mg can be used before studying to help memorize material or taken with Uridine to boost memory. Choline supplements are more effective than folate and B6 supplements, which work only in conjunction with the nutrient.

Soy free Alpha GPC

Alpha GPC that does not contain soy is a superior option, even for those who do not have an allergy to soy. Instead of soy lecithin, which is included in major competitors’ products, their Alpha GPC comes from sunflower lecithin. This is significant since the extraction of lecithin from sunflowers is accomplished by the use of a cold press, whereas the extraction of lecithin from soy is accomplished through the use of harsh chemicals that are associated with undesirable side effects.

Brain Health, Memory, Nervous System

Brain health, memory, nervous system, heart, liver, metabolism & muscle support. Dr. Maxwell’s Alpha GPC Choline + Uridine Mr Happy stack is an excellent source of choline, an essential nutrient needed for optimal health. Choline plays a key role in many processes and is required to make acetylcholine, a neurotransmitter involved in memory, muscle movement and recovery, regulating heartbeat and other basic functions.

Without Inactive Ingredients

The one and only alternative to a veggie capsule that does not contain any inactive substances. Silicon dioxide, stearic acid, magnesium stearate, starch, and other potentially harmful components are not included in any product sold by Dr. Maxwell because their primary focus is on achieving the highest possible level of wellbeing for their customers.

2. Choline Supplement

Jarrow Formulas Citicoline (CDP Choline) is an odorless, virtually tasteless white powder derived from soy lecithin. It promotes healthy nerve cell membrane function and increases phosphatidylcholine levels in the brain, which supports cognitive function, alertness and memory formation.

Attention Performance

It has been demonstrated that healthy adults and adolescents who take citicoline have improved attention performance. Additionally, the formula encourages the creation of neurotransmitters that have a role in cognitive processes (acetylcholine, dopamine, norepinephrine).

Brain Energy

Citicoline, also known as stabilized CDP choline, is an intermediate that occurs naturally and plays a role in the production of phosphatidylcholine, a significant component of the grey matter of brain tissue; The addition of citicoline helps the metabolism of the brain’s fuel.

Convenient Capsules

You should take one capsule with each meal, with a maximum of two capsules per day, however you should only take one capsule with each meal. The recommended dosage is one capsule with each meal. You should take one capsule with each meal rather than following the advice of your qualified healthcare expert if they recommend something else.

Superior Nutrition and Formulation

Jarrow Formulas was founded with the purpose of assisting patients in realizing their full health potential by formulating dietary supplements that are unrivaled in terms of their level of effectiveness, level of quality, and cost. When a customer purchases something from us, they may be certain that it is genuine, of good value, and will fulfill its intended purpose.

3. Choline Bitartrate 500mg

CDP-Choline, also known as Vitamin Bp 9.9 and choline bitartrate, is a natural nootropic supplement that can help you feel sharper and more focused. Scientific studies have shown that CDP-Choline helps the body convert carbohydrates into acetylcholine (1) (2) (3), which is involved in helping your brain cells communicate with each other, support your thinking processes and optimize your alertness when taking CDP-Choline supplements.

500MG Of Choline For Pregnant & Breastfeeding Mothers

Nestled Nature’s Gifts Choline supplementation includes 500 milligrams of L+ choline bitartrate, which is an essential nutrient for nursing and pregnant women. Choline helps to ensure that a pregnant woman’s diet is healthy and well-balanced, which in turn promotes appropriate prenatal development and growth. Consuming choline when nursing is another way to continue providing beneficial health benefits to your child.

Overall Support

Ingestion of a suitable amount of choline, in conjunction with a diet that is both healthy and balanced, is beneficial to the liver. Fatty acids are an essential source of energy for both the body and the brain, and choline plays a crucial role in the metabolism of these acids.

Socially Conscious Supplements

In addition to not including any of the allergens that cause the majority of allergic reactions, their Choline does not include any genetically modified organisms, gluten, soy, or animal ingredients in its formulation. It is created in their facility, which is certified to meet GMP and NSF standards, and it is tested by a Third Party to ensure that it is of the greatest quality possible.

Supports Brain and Nervous System

Choline is an essential chemical that can be found in the neurotransmitters throughout your body. By supplying your body with additional choline, taking choline in supplement form can help to support the health of your neurological system by supplying your body with additional choline.

4. Andrew Lessman PC Liver & Brain

PhosphatidylCholine is the most important building block for healthy liver and brain structure and function. From helping you avoid memory loss associated with age, to balancing moods, PC helps to maintain clear thinking at any age. PC is vital for the structural integrity of cell membranes, keeping your skin soft and supple. It also supports the body’s cholinergic system by converting to acetylcholine, a vital neurotransmitter that is key to optimal brain function and memory.

Superior 100% Pure Bio-Active Ingredients

Phosphatidylcholine and choline are both provided, in addition to a number of other vital phospholipids and plant-based Omega-3 fatty acids derived from ahiflower oil. Contains NO Milk; Dairy Free; Gluten Free; NO Yeast; NO Corn; NO Wheat; NO Sodium; NO Salt; NO Sugar; NO Cholesterol; NO Color; NO Preservatives; NO Additives Manufactured This item contains soy.

Concentrated, Stable Source Of The Most Important Phospholipids

Delivers the predominant phospholipid in the brain and liver. Supports the creation of all brain and liver cells, and the production of their most important neurotransmitter – Acetylcholine. Helps support the retention of their brain’s remarkable abilities and combat those normal, age-related changes in cognitive functions. Empowers the liver to rebuild and regenerate its hard-working tissues.

Unsurpassed Purity, Quallity, & Efficacy. Won’t Upset Your Stomach!

For 40+ years ProCaps products have contained NO additives of any kind. NO binders, fillers, lubricants, stabilizers, flowing agents, preservatives or artificial colors. Easy-to-swallow capsules (NO tablets) deliver only the MOST bioactive vitamins, minerals & ingredients in an ultra-fine micro-granulated powder for fast, complete absorption & maximum effectiveness. Non-acidic formula is gentle even on most sensitive stomachs.

Manufacturer Direct & Made In USA

ProCaps formulates, manufactures, and packages ALL of its products in ProCaps’ own laboratory and manufacturing plant in Nevada, USA. Unlike other nutritional supplement brands that utilize contract manufacturers, ProCaps controls every aspect of its products – from formulation design to ingredient sourcing, production techniques, and quality control – making ProCaps’ supplements the purest, safest, and most effective all-natural supplements available.

5. NOW Supplements, Alpha GPC 300 mg

NOW® Supplements Alpha-GPC 300 mg offers ultra-pure (99.6%) alpha-glycerophosphocholine in a hypromellose capsule (HPMC) to provide a bioavailable source of choline. Alpha GPC is the natural precursor to acetylcholine, an essential neurotransmitter in the central and peripheral nervous system. It is regularly used to support healthy brain function, as well as many other benefits.

Supports Mental Acuity

Supports Mental Acuity is a daily multivitamin, mineral and botanical supplement that promotes normal cognitive function, memory and focus. It is formulated with a unique blend of brain-boosting nutrients to help maintain brain health, including choline, inositol and vitamins B6 and A. Powerful antioxidants support healthy neurotransmitter function, while omega-3 fats help reduce inflammation throughout your body.


Free from the common allergens of dairy, eggs, wheat and nuts. These products contain no gluten and are made without ingredients derived from genetically modified organisms (GMOs). Made on dedicated equipment, in a separate facility and with the utmost care to avoid these common allergens.

GMP Quality Assured

NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including their laboratory/testing methods (for stability, potency, and product formulation), production facilities, and packaging. NPA inspectors also audit their operating practices to ensure that all employees are properly trained in quality control procedures. This assures you that NOW products will meet the high standards you expect from us.

Bioavailable Source of Choline

Choline is essential for the maintenance of cell membranes, transmitting nerve impulses and the production of acetylcholine, a neurotransmitter. BIOAVAILABLE SOURCE OF CHOLINE provides 600 mg of Alpha GPC per serving.

6. Alpha GPC Choline Capsules

Are you worried about your ability to recall important things or to focus on your most important tasks? Are you looking for a way to improve your memory and feel more optimistic about getting through the day? Are you interested in adding choline to your diet to help you reach your goals? If so, Double Wood Supplements has an all-natural answer for you with its Alpha GPC Choline Capsules. Their products are designed not just for health, but also for longevity. And their Alpha GPC Choline Capsules are specifically made at a high purity level to fuel brain function, boost memory, and lift mood naturally.

Supports Acetylcholine Levels

Their Alpha GPC is a natural precursor to acetylcholine, which is a neurotransmitter that helps support memory and general brain function. Acetylcholine is one of the neurotransmitters that helps support brain function. Alpha GPC has been shown to have positive effects on brain health, particularly as one advances in age.

Powerful Bioavailable Choline Support

Alpha GPC is the most bioavailable form of Choline currently available. Choline is a water-soluble nutrient which acts as a precursor to the neurotransmitter Acetylcholine, making Double Wood’s Alpha GPC Choline Capsules easily absorbed by the body and fast acting.

Monthly Supply

If you follow the dosage instructions that are printed on the label of each bottle of the supplement, you will have enough capsules to experience the potential benefits of their Alpha GPC Choline supplement for an entire month. The label of each bottle of the supplement contains these instructions. These directions are printed on the label that is affixed to the bottle.

USA Proud

All Doublewood supplements are Manufactured and tested for safety and quality in the USA, ensuring that only the highest quality ingredients are delivered to you. They are focused on giving you a natural, vegan-friendly, and GMO-free supplement you can trust.

7. Liver Cleanse Detox & Repair Formula

What makes the Liver Cleanse Detox & Repair Formula so unique is that it includes 5 proven liver repairing herbs known for enhancing liver function and promoting healthy liver tissue. This supplement is packed with ingredients like Milk Thistle, Turmeric, Dandelion Root and more for a powerful detoxification support. The formula is lab tested for heavy metals and pesticides to ensure only the highest quality ingredients go into your body.

Premium Milk Thistle

This premium milk thistle extract is grown and cultivated in Europe using a patented process to preserve the six key silymarin isomers that studies have shown to be important for liver health. This high-strength liver health formula contains 250 milligrams of this milk thistle extract.

Detox & Deload

Their liver support supplement is one of the most effective formulas on the market, and was created by experts to focus on liver cleanse, detox and repair for women and men who want to maintain their liver health and keep enzymes within the normal range.

Effective Antioxidants

Milk thistle has been combined with a number of other premium, research-backed ingredients, including artichoke leaf extract, dandelion root, beet root, and protease, in order to provide a gentle cleanse. This has been done both to ensure that you get the best possible results and to maximize the benefits that milk thistle has to offer.

Overall Wellness

If you take just two of these easy-to-swallow capsules every day, you will not only relieve the strain on your liver and protect it from the stresses caused by toxins, but you may also experience an increase in energy levels, as well as improvements in the health of your gut and immune system.

Best Choline Supplement For Fatty Liver-Buying Guide

Choline Supplement For Fatty Liver

Before you buy a choline supplement, there are some considerations to keep in mind. Choline is an essential nutrient that is naturally present in many foods. However, it can also be taken as a supplement that can provide additional benefits.

Here are some considerations to keep in mind when purchasing a choline supplement:

The type of choline

There are two different types of choline supplements: CDP-choline (Citicoline) and Alpha GPC (Alpha Glycerylphosphorylcholine). Both of these work well but they affect the body differently. CDP-choline is more commonly used in supplements and has been shown to increase acetylcholine levels in the brain and prevent damage from stress and alcohol consumption.[1] Alpha GPC has been shown to improve liver function as well as reduce oxidative stress.[2]


The recommended dosage for CDP-choline is 500 mg three times per day for one month with a maximum daily dosage of 1,500 mg.[3] For Alpha GPC, the recommended dose is 300 mg three times per day up to 1,200 mg per day.[4] If you have any pre-existing medical conditions or are taking any medications, consult your doctor before taking any supplements.


You want to make sure that your choline source is pure. This means no fillers or ingredients that will interfere with your body’s ability to absorb it. A good company will tell you exactly what’s in their product so that you know what you’re getting out of every dose.


The level of quality of the product is what establishes whether or not it is safe to use in everyday situations. You should make it a point to avoid goods that have been created using chemical solvents or that contain pollutants because they may be harmful to your health. You should also avoid things that have pollutant ingredients.


Some manufacturers do not provide adequate information about their products, which means that they do not tell consumers if their products are safe or not. If you want to buy a good quality choline supplement, always look for brands that have been certified by regulatory bodies such as FDA or NSF International. These organizations have strict guidelines when it comes to manufacturing supplements and they only approve those products that meet these guidelines.

Best Choline Supplement For Fatty Liver- FAQs

What foods are high in choline?

There are various animal-based foods that include choline, such as eggs, fish, red meat, chicken, and liver. Choline is found in nuts and seeds, and one serving of peanuts provides 24 mg. This is an excellent source for vegans seeking a vegan choice.

Non-animal sources of choline include almonds, cashews, and pistachios. You can also take a supplement if you’re a vegetarian or vegan and want to increase your choline consumption.

How much choline should I take for fatty liver?

There is not enough information available to create a Recommended Daily Allowance (RDA) for choline at this time. [2] The Food and Nutrition Board created what they call an Adequate Intake (AI) for choline with the goal of preventing liver damage as their primary motivation. AI: The Adequate Intake for adults over the age of 19 is 550 milligrams per day for men and 425 milligrams per day for women.

How long does it take for choline to start working?

Within an hour of administration, choline bitartrate causes an increase in choline levels in the blood plasma of humans [57, 58]. Choline concentrations in the brain peak approximately two hours after ingestion and remain elevated for at least three hours after ingestion [59, 60]. The effects that choline has on the cholinergic peripheral system reach their peak between one and two hours after consumption [46].

Who should take choline supplements?

Schizophrenia, athletic performance, and Alzheimer’s illness are only some of the conditions that fall into this category. According to the Institute of Medicine, healthy adult women require a daily intake of 425 milligrams of choline from their food, with this requirement increasing to 450 milligrams if they are pregnant or breastfeeding (550 mg.) Daily dosing for adult males should be 550 mg.


Foods like meat, cow liver, fish, poultry, and eggs should be the initial way to include choline into your diet, but supplements are your next best solution when you feel you need more.

All of the choline supplements on our list are top selections, but one vitamin easily outranks the rest.

Its all-inclusive makeup makes it easy to use for everyone regardless of age and health issues, and it is widely acknowledged as one of the safest supplements to consume. No other product on the market can claim so many virtues in one stack.

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